Downtown San Francisco Vacations from $428
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Your Downtown San Francisco Vacation
Experience everything Downtown San Francisco has to offer with a tailor-made Downtown San Francisco vacation package. From its history and shopping to its dining, prepare to be captivated by this busy neighborhood. When it's time to see the sights, you'll find plenty of big-name attractions nearby including Pier 39, Alcatraz Island and Lombard Street. Tick off one, two or all during your trip to Downtown San Francisco. Don't just think about it — turn it into reality! Book your ultimate Downtown San Francisco vacation with Expedia and experience travel your way.
The Latest Downtown San Francisco Vacation Packages
Bay Landing San Francisco Airport Hotel
Reviewed on Nov 23, 2025
Marbella Lane Triplex San Jose
Reviewed on Nov 11, 2025
1 Hotel San Francisco
Reviewed on Nov 10, 2025
Where to stay in Downtown San Francisco
Union Square
Major tourist destination in downtown San Francisco, Union Square boasts shopping, hotels, and theaters. Explore department stores, boutiques, and galleries, or catch a performance at various theaters. Enjoy the Dewey Monument and stunning views from nearby hotels. Easily accessible via cable car lines, buses, and subway systems.
Downtown San Francisco Hotel Deals
Hilton San Francisco Financial District
Best ever thank you
Reviewed on Nov 17, 2025
Holiday Inn Golden Gateway by IHG
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Reviewed on Nov 23, 2025
Hyatt Regency San Francisco
Room is excellent
Reviewed on Nov 20, 2025
Discover the most popular places to visit in Downtown San Francisco
Moscone Convention Center
During your trip, find out what's happening at Moscone Convention Center, a top convention center in San Francisco. Discover the fascinating museums and shops in this vibrant area.
Oracle Park
Whether or not you’re a baseball fan, this charming ballpark with outstanding views should be on your San Francisco sightseeing list.
Ferry Building
During your trip to San Francisco, you can enjoy retail therapy at Ferry Building. Discover the acclaimed theater scene and notable monuments in this vibrant area.
Things to do
California Academy of Sciences Daytime Admission
Alcatraz Visit with Night Option and SF Bay Cruise
San Francisco City Lights Cruise (2-hours)
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- San Francisco Vacations
- Grace Cathedral
- San Francisco Museum of Modern Art
- Warfield Theatre
- San Francisco City Hall
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- SHN Curran Theatre
- Visit San Francisco
- American Conservatory Theater
- Luggage Store Gallery
- Westin St Francis Hotel Glass Elevators
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- Van Ness Avenue
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- Palace Hotel
- Bill Graham Civic Auditorium
- Crocker Galleria
- Yerba Buena Ice Skating Center
- Crocker Bank Building
- The Museum Store
- St. Mary Square
- Cable Car Museum
- The Regency Ballroom